This note presents comparative and automated system-based data on CTS™ Detachable Dynabeads™ CD3/CD28, which offer a one-step T cell isolation and activation approach with the added benefit of active release. The findings show comparable activation and expansion to traditional passive beads, with higher flexibility in timing bead removal. When used with the CTS™ DynaCellect™ Magnetic Separation System, this solution delivers high-purity T cells with preserved early memory phenotypes and supports scalable, consistent, closed-system manufacturing.
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